Epidemiological Studies of Recovery


Recovery From Schizophrenic Psychoses Within the Northern Finland 1966 Birth Cohort

2005
Research Based

  • This study reports the extent of recovery from schizophrenia in a population-based cohort and has data that indicates, at least until age 35, that complete recovery from schizophrenia is rare.
  • Lauronen, Erika, koskinen, Johanna, Veijola, Juha, & Isohanni, Matti. (2005). Recovery From Schizophrenic Psychoses Within the Northern Finland 1966 Birth Cohort. Journal of Clinical Psychiatry, 66(3), 375-383.

 

Do Patients with Schizophrenia Ever Show Periods of Recovery? A 15-Year Multi-Follow-up Study

2005
Research Based

  • This 15-year, prospectively designed follow-up study compares individuals with schizophrenia with individuals with psychosis and without to show that many individuals with schizophrenia do, in fact, show intervals of recovery.
  • Harrow, Martin, Grossman, Linda S., Jobe, Thomas H., and Herbener, Ellen S. (2005). Do Patients with Schizophrenia Ever Show Periods of Recovery? A 15-Year Multi-Follow-up Study. Schizophrenia Bulletin, 31(3), 723-734.

 

Recovery from psychotic illness: a 15- and 25-year international follow-up study

2001
Research Based

  • This study aims to improve cross-cultural comparisons of course and outcome in schizophrenia.
  • Harrison, G., Hopper, K., Craig, T., et al. (2001). Recovery from psychotic illness: a 15- and 25-year international follow-up study. British Journal of Psychiatry, 178, 506-517.

 

Time to recurrence after recovery from major depressive episodes and its predictors

2003
Research Based

  • A 6-year multi-centre prospective serial follow-up study was done with participants with previously untreated unipolar major depression. An unfortunate conclusion was that less than half of the patients can expect to remain virtually symptom-free for 2 years or more after recovery from the depressive episode.
  • Kanai T., Takeuchi H., Furukawa T.A., Yoshimura R., et al. (2003). Time to recurrence after recovery from major depressive episodes and its predictors. Psychological Medicine, 33(5), 839-345.

 

Operational criteria and factors related to recovery from schizophrenia

2002
Research Based

  • Although schizophrenia is often viewed pessimistically, retrospective and prospective studies with both chronic and recent onset patients suggest that schizophrenia has a heterogeneous course, which can be favorably influenced by comprehensive and continuous treatment and personal factors.
  • Liberman, Robert Paul, Kopelowicz, Alex, Ventura, Joseph, and Gutkind, Daniel. (2002). Operational criteria and factors related to recovery from schizophrenia. International Review of Psychiatry, 14(4), 256-272.

 

Lessons learned from three studies of recovery from schizophrenia

2002
Research Based

  • Findings from studies carried out in Norway reveal that full recovery from schizophrenia was rare and that stability of recovery was transient and fragile.
  • Torgalsboen, Anne-Kari, and Rund, Bjorn Rishovd. (2002). Lessons learned from three studies of recovery from schizophrenia. International Review of Psychiatry, 14(4), 312-317.

 

Two-year syndromal and functional recovery in 219 cases of first episode major affective disorder with psychotic features

2000
Research Based

  • In this study, the authors determined the rate and latency of both syndromal and functional recovery after the initial hospitalization of patients with first-episode psychotic affective disorders. The findings suggest that these very common psychotic illnesses can carry a grave functional prognosis from the initial episode and first hospitalization.
  • Tohen M, Hennen J, Zarate CM, Baldessarini RJ, et al. (2000). Two- year syndromal and functional recovery in 219 cases of first episode major affective disorder with psychotic features. American Journal of Psychiatry, 157(2), 220-228.

 

Prolonged recovery in first-episode psychosis

1998
Research Based

  • This paper examined the data of 227 individuals on enduring positive symptoms in first-episode psychosis.
  • Edwards, J., Maude, D., McGorry, P., Harrigan, S., & Cocks, J. (1998). Prolonged recovery in first-episode psychosis. British Journal of Psychiatry, 172 (Suppl. 33) 107-116.

 

The Maine and Vermont three-decade studies of serious mental illness: I. Matched comparisons of cross-sectional outcome
The Maine and Vermont three-decade studies of serious mental illness: II. Longitudinal course comparisons

1995
Research Based

  • These two articles provide accounts and comparisons of the outcomes of individuals from Maine and Vermont followed over three decades of study in the Vermont Longitudinal Project.
  • DeSisto, M. J., Harding, C. M., McCormick, R. V., Ashikaga, T., & Brooks, G. W. (1995a). The Maine and Vermont three-decade studies of serious mental illness: I. Matched comparisons of cross-sectional outcome. British Journal of Psychiatry, 167(3), 331-338.
  • DeSisto, M. J., Harding, C. M., McCormick, R. V., Ashikaga, T., & Brooks, G. W. (1995b). The Maine and Vermont three-decade studies of serious mental illness: II. Longitudinal course comparisons. British Journal of Psychiatry, 167(3), 338-341.

 

The Vermont longitudinal study of persons with severe mental illness, I. Methodology, study sample, and overall status 32 years later

1987
Research Based

  • The authors report the latest findings from a 32-year longitudinal study of 269 back-ward patients from Vermont State Hospital. This intact cohort participated in a comprehensive rehabilitation program and was released to the community in a planned deinstitutionalization effort during the mid-1950s.
  • Harding, C.M, Brooks G.W., Ashikaga, T., Strauss, J.S., & Breier, A. (1987). The Vermont longitudinal study of persons with severe mental illness, I. Methodology, study sample, and overall status 32 years later. American Journal of Psychiatry, 144, 718-726.

 

The Vermont longitudinal study of persons with severe mental illness, II. Long-term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia

1987
Research Based

  • The paper presents the findings of a long-term follow-up study of 118 patients from Vermont State Hospital who, when rediagnosed retrospectively, met DSM-III criteria for schizophrenia at their index hospitalization in the mid-1950s.
  • Harding, C.M, Brooks G.W., Ashikaga, T., Strauss, J.S., & Breier, A. (1987). The Vermont longitudinal study of persons with severe mental illness, II. Long-term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia. American Journal of Psychiatry, 144, 727-735.